December 11, 2017

A figure from our recent mSphere paper was chosen as the Cover Image for November/December.



November 28, 2017

New Publication! LaGrow AL, Coburn PS, Miller FC, Land C, Parkunan SM, Luk BT, Gao W, Zhang L, Callegan MC. A novel biomimetic nanosponge protects the retina from the Enterococcus faecalis cytolysin. mSphere 2017;e00335-17.


November 22, 2017

Our new mSphere paper is featured in Science Daily.

American Society for Microbiology. “Nanosponges show promise for potentially blinding eye infections.” ScienceDaily, 22 November 2017.


November 7, 2017

Erin has been accepted as an NEI Vision Science Pre-Doctoral Trainee for the DMEI/OUHSC/OMRF Vision Science Training Program (T32)! Congratulations Erin!!!

September 29, 2017

At the 11th Annual OU Vision Student and Postdoctoral Fellow Workshop, Erin presented Characterization of PMN Dysfunction During Bacillus cereus Endophthalmitis and Mursalin presented Unconventional Toll-like Receptor 4 (TLR4) Agonists in Gram-positive Bacillus cereus.

August 10, 2017

Congratulations Mursalin on passing your General Exam!

July 2017

Our lab is featured in the spring/summer edition of OU Medicine.


June 9, 2017

An official welcome to the Summer Crew…Ty Dilley (OUHSC Medical Student), Austin LaGrow (OUHSC Medical Student), Melissa Penton (INBRE Student from East Central University), Parth Patel (Oklahoma School for Science and Math), Daniel Astley (University of Central Oklahoma), Caleb Astley (Deer Creek/Francis Tuttle), and Emma Howard (Edmond Memorial).

June 2-3, 2017

At ASM Microbe 2017 in New Orleans, Dr. Coburn presented A Novel Biomimetic Nanosponge Protects the Retina from the Enterococcus faecalis Cytolysin (Coburn, LaGrow, Miller, Luk, Zhang, Callegan), and Dr. Callegan presented Transcriptome Analysis of Bacillus cereus in Ocular and Laboratory Environments (Callegan, Coburn, Enty, Land, LaGrow, Miller).

May 26, 2017

New Publications photo: A portion of a heat map of the transcriptomes of B. cereus cultivated in ocular and laboratory environments. This data will be presented next week at ASM in New Orleans. Illumina MiSeq Next Gen sequencing was performed and data analyzed with the CLC Genomics Workbench (Qiagen) at the OUHSC Laboratory for Molecular Biology and Cytometry Research.

May 7, 2017

Dr. Coburn was a co-author on the following presentation: Bhatti F, Kassa N, Kung J, Coburn P. Effect of Surfactant Protein A on Retinal Cytokines and Microglia in Systemic Inflammation. Association for Research in Vision and Ophthalmology 2017 Annual Meeting, Baltimore MD.

May 5, 2017

Dr. Callegan presented Messaging Yourself: Increasing Your Visibility & Crafting Your Message and Maximizing Your MPG (Mission-Planning-Goals) at the Leadership Development Program for Women at the Association for Research in Vision and Ophthalmology 2017 Annual Meeting, Baltimore MD.

May 1, 2017

An official welcome to Erin Arroz, Graduate Student in the Department of Microbiology and Immunology, to the lab!

March 20, 2017

New Publication!

Callegan MC, Parkunan SM, Randall CB, Coburn PS, Miller FC, LaGrow AL, Astley RA, Land C, Oh S-Y, Schneewind O. The Role of Pili in Bacillus cereus Intraocular Infection. Exp Eye Res 159:69-76, 2017.


March 8, 2017

New News photo courtesy of Craig Land, Dr. Coburn, and the Oklahoma Medical Research Foundation Imaging Core. Bacillus cereus flagella, 50,000X magnification.

February 8, 2017

Dr. Callegan presented Endogenous Endophthalmitis: The Beast Within at Asia-ARVO 2017 in Brisbane.

October 14, 2016

Mursalin presented Sex as a Biological Variable in Gram-Positive Endophthalmitis at the 10th Annual OU Vision Student & Postdoctoral Fellow Workshop.

September 20, 2016

Dr. Callegan presented Bacterial Endophthalmitis: BOB’s Your Uncle at the Department of Microbiology and Immunology’s Seminar Series

July 15, 2016

Sujana presented A Novel Biomimetic Nanosponge Protects the Retina from the Enterococcus faecalis Cytolysin at the Oklahoma IDeA Network for Biomedical Research Excellence (OK-INBRE) Summer Research Program’s final poster session.

July 13, 2016

We held our Lab Retreat today at the Oklahoma City Zoo Treehouse. Great meeting facilities. Everyone presented their summer projects and research plans for the next year. A little bit of Poke-hunting and a lot of great science at the OKC Zoo!

Dr. Miller, Mursalin, Daniel, Haley, Craig, Sujana, Austin, Dr. Coburn, Dr. Callegan, Morgan, and Roger.

June 12, 2016

New publication!
Parkunan SM, Randall CB, Astley RA, Furtado GC, Lira SA, Callegan MC. CXCL1, but not IL-6, significantly impacts intraocular inflammation during infection. J Leukocyte Biol 2016.
In press

June 1, 2016

An official welcome to the Summer Crew…Morgan Enty (OUHSC Medical Student), Victoria Smith (OUHSC Medical Student), Sujana Rupakheti (INBRE Student from Cameron University), Meghna Shankar (Baylor University), Daniel Astley, and Haley Callegan…and a bittersweet “see you later” (never goodbye!) to Dr. Madhu Parkunan and Nanette Wheatley Albrecht.

May 20, 2016

New publication!
Coburn PS, Wiskur BJ, Miller FC, LaGrow AL, Astley RA, Elliott MH, Callegan MC. Bloodstream-To-Eye Infections Are Facilitated by Outer Blood-Retinal Barrier Dysfunction. Plos One 2016.
In press

May 13-14, 2016
The typical Oklahoma stormy weather disrupted the graduation festivities in Norman on the 13th, but Madhu was hooded by Dr. Callegan the next day at the OUHSC Graduate College Convocation. Dr. Parkunan’s Ph.D. thesis is titled “Contribution of Host Innate Responses to the Pathogenesis of Bacillus cereus Endophthalmitis”. Her thesis contains her three first-author papers in 2014, 2015, and 2016. Congratulations Dr. Salai Madhumathi Arasi Parkunan!

May 5, 2016

New publication!
Astley RA, Coburn PS, Parkunan SM, Callegan MC. Modeling intraocular bacterial infections. Prog Retina Eye Res 2016.
In press online version

May 2, 2016

The following research was presented today at ARVO 2016 in Seattle:
Coburn PS, Miller FC, Land C, LaGrow AL, Callegan MC. Cereolysin O influences TLR4-dependent retinal gene expression during Bacillus cereus endophthalmitis.
Callegan MC, Coburn PS, Zhao H, Rybenkov VV. Role of Pseudomonas aeruginosa Condensins in Corneal Infection.

April 30, 2016
Dr. Callegan gave a talk entitled Mentorship and Sponsorship at the ARVO Women’s Leadership Development Program in Seattle.

April 28, 2016
Madhu successfully defended her Ph.D. Dissertation!

April 24, 2016
New publication! Parkunan SM and Callegan MC. The Pathogenesis of Bacterial Endophthalmitis. In Endophthalmitis, Durand, Miller, and Young eds. Springer International Publishing Switzerland. 2016

April 1, 2016
New publication in American Journal of Ophthalmology Case Reports
Venincasa VD, Callegan MC, Astley RA, Siatkowski RM. Contact Lens-related Polymicrobial Keratitis from Pantoea agglomerans and Escherichia vulneris. Am J Ophthalmol Case Rep (2016, in press). NIH Public Access Compliance: In process at NIHMS [NIHMS771299].

March 9, 2016
An official welcome to MD Huzzatul Mursalin, graduate student in the Department of Microbiology and Immunology, to the lab!

March 2, 2016
Welcome to our new website!